[Q10] Genome rearrangements: algebraic distance, classic rearrangement operations

According to the definition of the permutation ρ = (u v)(π_chrΓv π_chrΓu) to perform two-break operations, which elements should u and v be, to turn π into σ?

 

1. u = -c, v = e
2. u = -c, v = -e
3. u = b, v = f
4. u = b, v = -f
5. None of the above.

Original idea by: Juan Felipe Hernández Albarracín.